coronavirus (HCoV-HKU1) Nucleoprotein/NP Protein Recombinant Protein | NP recombinant protein

Recombinant Human coronavirus (HCoV-HKU1) Nucleoprotein/NP Protein (His Tag)

Cat. Num. AAA2569546

• Purity: >90% as determined by SDS-PAGE
• Synonyms: coronavirus (HCoV-HKU1) Nucleoprotein/NP Protein; Recombinant Human coronavirus (HCoV-HKU1) Nucleoprotein/NP Protein (His Tag); NP recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile 40mM PB, 500mM NaCl, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
• Sequence: Met1-Ala441

• Species: Human coronavirus (HCoV-HKU1)
• Tag: N-His
• Endotoxin: Please contact us for more information.
• Protein Construction: A DNA sequence encoding the Human coronavirus (HCoV-HKU1) Nucleoprotein (YP_173242.1)(Met1-Ala441) was expressed with a polyhistide tag at the N-terminus.
• Preparation and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.; This product is provided as lyophilized powder which is shipped with ice packs.

SDS-Page

Related Product Information for NP recombinant protein

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a test tool.

Product Categories/Family for NP recombinant protein

Virus related Protein

NCBI and Uniprot Product Information

• NCBI GI #: 56807330
• NCBI GeneID: 3200423
• NCBI Accession #: YP_173242.1
• NCBI GenBank Nucleotide #: NC_006577.2
• UniProt Accession #: Q5MQC6
• Molecular Weight: 49,142 Da
• NCBI Official Full Name: nucleocapsid phosphoprotein
• NCBI Official Symbol: N
• NCBI Protein Information: nucleocapsid phosphoprotein
• UniProt Protein Name: Nucleoprotein
• Protein Family: Nucleoprotein
• UniProt Gene Name: N
• UniProt Synonym Gene Names: NC; Protein N

Uniprot Description

Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid. Interaction with the M protein leads to the formation of virus particles. Binds to cellular membranes and phospholipids. Elicits cell-mediated immunity. May play roles in viral transcription and translation, and/or replication ().