Nucleoprotein (N) Recombinant Protein | N recombinant protein
Recombinant Lassa virus Nucleoprotein (N)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Nucleoprotein (N); Recombinant Lassa virus Nucleoprotein (N); N recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-570. Full Length
Sequence
MSASKEVRSCLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKQKRDDGDLKRLRDLNQAVNNLVELKSTQQKSVLRVGTLSSDDLLILAADLEKLKSKVTRTERPLSSGVYMGNLSSQQLDQRRALLNMIGMTGVSGGGKGASNGIVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNSSDLDRLSQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKSLGMFVSDTPGERNPYENILYKICLSGDGWSYIASRTSIVGRAWENTVVDLEQDNKPQKIGNGGSNKSLQSAGFAAGLIYSQLMTLKDFKCFNLIPNAKTWMDIEGRPEDPVEIALYQPSSGCYVHFFREPTDLKQFKQDAKYSHGRDVTDLFAAQPGLTSAVIEALPRNMVITCQGSEDIRKLLESQGRRDIKLIDITLSKADSRKFENAVWDQFKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLDAKVLRVVLPRDMVFRTSTPKVVL
Species
Lassa virus (strain GA391) (LASV)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
Uniprot Description
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation.
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Product Notes
The Nucleoprotein (N) n (Catalog #AAA1144758) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-570. Full Length. The amino acid sequence is listed below: MSASKEVRSC LWTQSLRREL SGYCSNIKLQ VVKDAQALLH GLDFSEVSNV QRLMRKQKRD DGDLKRLRDL NQAVNNLVEL KSTQQKSVLR VGTLSSDDLL ILAADLEKLK SKVTRTERPL SSGVYMGNLS SQQLDQRRAL LNMIGMTGVS GGGKGASNGI VRVWDVKNAE LLNNQFGTMP SLTLACLTKQ GQVDLNDAVQ ALTDLGLIYT AKYPNSSDLD RLSQSHPILN MIDTKKSSLN ISGYNFSLGA AVKAGACMLD GGNMLETIKV SPQTMDGILK SILKVKKSLG MFVSDTPGER NPYENILYKI CLSGDGWSYI ASRTSIVGRA WENTVVDLEQ DNKPQKIGNG GSNKSLQSAG FAAGLIYSQL MTLKDFKCFN LIPNAKTWMD IEGRPEDPVE IALYQPSSGC YVHFFREPTD LKQFKQDAKY SHGRDVTDLF AAQPGLTSAV IEALPRNMVI TCQGSEDIRK LLESQGRRDI KLIDITLSKA DSRKFENAVW DQFKDLCHMH TGVVVEKKKR GGKEEITPHC ALMDCIMFDA AVSGGLDAKV LRVVLPRDMV FRTSTPKVVL. It is sometimes possible for the material contained within the vial of "Nucleoprotein (N), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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