Mouse myosin IXB ELISA Kit | MYO9B elisa kit
Mouse Myosin-IXb, MYO9B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MYO9B: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho. Genetic variation in MYO9B is the cause of susceptibility to celiac disease type 4 (CELIAC4). It is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins. In its classic form, celiac disease is characterized in children by malabsorption and failure to thrive. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs; Actin-binding; Motility/polarity/chemotaxis; Motor
Cellular Component: filamentous actin; ruffle; filopodium tip; cytoskeleton; membrane; perinuclear region of cytoplasm; lamellipodium; cytoplasm; actin filament; cell cortex; intracellular; myosin complex
Molecular Function: zinc ion binding; metal ion binding; ATPase activity; motor activity; nucleotide binding; actin-dependent ATPase activity; ADP binding; actin binding; GTPase activator activity; actin filament binding; microfilament motor activity; calmodulin binding; ATP-dependent protein binding; ATP binding
Biological Process: monocyte chemotaxis; establishment of cell polarity; metabolic process; actin-myosin filament sliding; signal transduction; macrophage chemotaxis; Rho protein signal transduction; positive regulation of GTPase activity
Research Articles on MYO9B
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Product Notes
The Mouse MYO9B myo9b (Catalog #AAA9330497) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330497 ELISA Kit recognizes Mouse MYO9B. It is sometimes possible for the material contained within the vial of "myosin IXB, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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