Rat myosin VA (heavy chain 12, myoxin) ELISA Kit | MYO5A elisa kit
Rat Myosin-Va, MYO5A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may play a role in secretory granule transport [RGD, Feb 2006]
Uniprot Description
MYO5A: Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. May also be required for some polarization process involved in dendrite formation. May be a homodimer, which associates with multiple calmodulin or myosin light chains. Binds MLPH and MYRIP. Interacts with RIPL2, the interaction is required for its role in dendrite formation. Detected in melanocytes. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Motility/polarity/chemotaxis
Cellular Component: Golgi apparatus; filopodium tip; lysosome; early endosome; actomyosin; cytosol; secretory granule; recycling endosome; synaptic vesicle; actomyosin, myosin complex part; photoreceptor outer segment; membrane; cell soma; cytoplasm; melanosome; peroxisome; myosin complex; vesicle; neuron projection; cell; endoplasmic reticulum; intermediate filament; actin filament; ruffle; axon; late endosome
Molecular Function: protein dimerization activity; motor activity; calcium ion binding; actin binding; calcium-dependent protein binding; calmodulin binding; microfilament motor activity; ATP-dependent protein binding; protein binding; SNARE binding; protein heterodimerization activity; syntaxin-1 binding; ATP binding; Rab GTPase binding
Biological Process: myelination; exocytosis; melanin metabolic process; metabolic process; pigmentation during development; long-chain fatty acid biosynthetic process; locomotion during locomotory behavior; odontogenesis; vesicle transport along actin filament; synaptic transmission; protein transport; visual perception; melanocyte differentiation; synapse organization and biogenesis; regulation of inositol-1,4,5-triphosphate receptor activity; neuromuscular process controlling balance; ER localization; actin filament-based movement; melanosome localization; melanosome transport; vesicle-mediated transport; melanin biosynthetic process; regulation of exocytosis; cellular response to insulin stimulus; pigmentation; insulin secretion; post-Golgi vesicle-mediated transport; secretory granule localization
Research Articles on MYO5A
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Product Notes
The Rat MYO5A myo5a (Catalog #AAA9321427) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321427 ELISA Kit recognizes Rat MYO5A. It is sometimes possible for the material contained within the vial of "myosin VA (heavy chain 12, myoxin), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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