Myosin Light chain Recombinant Protein | MYLPF recombinant protein
Recombinant Human Myosin Light chain, Phosphorylatable, Fast Skeletal Muscle
Gene Names
MYLPF; MRLC2; MYL11; HUMMLC2B
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Myosin Light chain; Recombinant Human Myosin Light chain; Phosphorylatable; Fast Skeletal Muscle; MYLPF Human; Fast Skeletal Muscle Human Recombinant; Myosin regulatory light chain 2 skeletal muscle isoform; Fast skeletal myosin light chain 2; MLC2B; MYLPF; MRLC2; MYL11; HUMMLC2B; MYLPF recombinant protein
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
MYLPF protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 100mM NaCl.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MAPKRAKRRT VEGGSSSVFS MFDQTQIQEF KEAFTVIDQN RDGIIDKEDL RDTFAAMGRL NVKNEELDAM MKEASGPINF TVFLTMFGEK LKGADPEDVI TGAFKVLDPE GKGTIKKKFL EELLTTQCDR FSQEEIKNMW AAFPPDVGGN VDYKNICYVI THGDAKDQE.
Sequence Length
169
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for MYLPF recombinant protein
Description: MYLPF produced in E Coli is a single, non-glycosylated polypeptide chain containing 189 amino acids (1-169 a.a) and having a molecular mass of 21.2kDa.MYLPF is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Myosin regulatory light chains, including MRCL3, MYLPF and MYL9, regulate contraction in smooth muscle and non-muscle cells via phosphorylation by MLCK (myosin light chain kinase). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the actin-activated myosin ATPase activity, thus regulating the contractile activity. MYLPF is vital for fast and slow skeletal muscle development.
Introduction: Myosin regulatory light chains, including MRCL3, MYLPF and MYL9, regulate contraction in smooth muscle and non-muscle cells via phosphorylation by MLCK (myosin light chain kinase). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the actin-activated myosin ATPase activity, thus regulating the contractile activity. MYLPF is vital for fast and slow skeletal muscle development.
Product Categories/Family for MYLPF recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,015 Da
NCBI Official Full Name
myosin regulatory light chain 2, skeletal muscle isoform
NCBI Official Synonym Full Names
myosin light chain, phosphorylatable, fast skeletal muscle
NCBI Official Symbol
MYLPF
NCBI Official Synonym Symbols
MRLC2; MYL11; HUMMLC2B
NCBI Protein Information
myosin regulatory light chain 2, skeletal muscle isoform; MLC2B; MYLPF; fast skeletal myosin light chain 2; myosin, light chain 11, regulatory
UniProt Protein Name
Myosin regulatory light chain 2, skeletal muscle isoform
Protein Family
UniProt Gene Name
MYLPF
UniProt Entry Name
MLRS_HUMAN
Uniprot Description
MYLPF: Myosin is an hexamer of 2 heavy chains and 4 light chains.
Protein type: Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: lysosomal membrane; muscle myosin complex
Molecular Function: structural constituent of muscle; calcium ion binding
Biological Process: skeletal muscle development; immune response
Research Articles on MYLPF
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Product Notes
The MYLPF mylpf (Catalog #AAA144351) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MAPKRAKRRT VEGGSSSVFS MFDQTQIQEF KEAFTVIDQN RDGIIDKEDL RDTFAAMGRL NVKNEELDAM MKEASGPINF TVFLTMFGEK LKGADPEDVI TGAFKVLDPE GKGTIKKKFL EELLTTQCDR FSQEEIKNMW AAFPPDVGGN VDYKNICYVI THGDAKDQE. . It is sometimes possible for the material contained within the vial of "Myosin Light chain, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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