Myosin Light Chain 9 Recombinant Protein | MYL9 recombinant protein

Recombinant Human Myosin Light Chain 9

Cat. Num. AAA144714

• Gene Names: MYL9; LC20; MLC2; MRLC1; MYRL2; MLC-2C
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Synonyms: Myosin Light Chain 9; Recombinant Human Myosin Light Chain 9; MYL9 Human; Myosin Light Chain 9 Human Recombinant; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2; smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; MYL9; MLC2; MRLC1; MYRL2; MGC3505; MYL9 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE.
• Form/Format: The MYL9 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 10% glycerol.; Sterile Filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MSSKRAKAKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDEYL EGMMSEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEASGFIHE DHLRELLTTM GDRFTDEEVD EMYREAPIDK KGNFNYVEFT RILKHGAKDK DD
• Sequence Length: 172

Related Product Information for MYL9 recombinant protein

Introduction: MYL9 is one of the numerous regulatory myosin light chains. Myosin which is a structural component of the muscle consists of 2 heavy chains and 4 light chains. MYL9 is a myosin light chain regulates muscle contraction by modulating the ATPase activity of myosin heads. MYL9 binds calcium and is activated by myosin light chain kinase. Regulatory myosin light chains regulate contraction in smooth muscle and non-muscle cells via phosphorylation by MLCK (myosin light chain kinase). Phosphorylation of regulatory myosin light chains is catalyzed by MLCK in the presence of calcium and calmodulin and it increases the actin-activated myosin ATPase activity, thus regulates the contractile activity.

Product Categories/Family for MYL9 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Myosin Light Chain

NCBI and Uniprot Product Information

• NCBI GI #: 29568111
• NCBI GeneID: 10398
• NCBI Accession #: NP_006088.2
• NCBI GenBank Nucleotide #: NM_006097.4
• UniProt Accession #: P24844; Q9BQL9; Q9BUF9; Q9H136; E1P5T6
• Molecular Weight: 13,866 Da
• NCBI Official Full Name: myosin regulatory light polypeptide 9 isoform a
• NCBI Official Synonym Full Names: myosin, light chain 9, regulatory
• NCBI Official Symbol: MYL9
• NCBI Official Synonym Symbols: LC20; MLC2; MRLC1; MYRL2; MLC-2C
• NCBI Protein Information: myosin regulatory light polypeptide 9; 20 kDa myosin light chain; myosin RLC; myosin regulatory light chain 1; myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 9; myosin regulatory light chain MRLC1; myosin, light polypeptide 9, regulatory
• UniProt Protein Name: Myosin regulatory light polypeptide 9
• Protein Family: Myosin regulatory light polypeptide
• UniProt Gene Name: MYL9
• UniProt Synonym Gene Names: MLC2; MRLC1; MYRL2; LC20
• UniProt Entry Name: MYL9_HUMAN

NCBI Description

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

MRLC1: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains. Smooth muscle tissues and in some, but not all, nonmuscle cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Contractile; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: stress fiber; muscle myosin complex; Z disc; cytosol

Molecular Function: structural constituent of muscle; calcium ion binding

Biological Process: axon guidance; muscle contraction; regulation of muscle contraction; ephrin receptor signaling pathway