V-Myc Myelocytomatosis Viral Oncogene Recombinant Protein | MYC recombinant protein
Recombinant Human V-Myc Myelocytomatosis Viral Oncogene
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
V-Myc Myelocytomatosis Viral Oncogene; Recombinant Human V-Myc Myelocytomatosis Viral Oncogene; MYC Human; V-Myc Myelocytomatosis Viral Oncogene Human Recombinant; MYC; CMYC; C-MYS; V-MYC; P64; MYC recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
Myc was lyophilized after extensive dialysis against PBS.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
MGSSHHHHHHSSGLVPRGSH MGSEFMEFLL GNPFSTPVGQ CLEKATDGSL QSEDWTLNME ICDIINETEEGPKDAIRALK KRLNGNRNYR EVMLALTVLE TCVKNCGHRF HILVANRDFI DSVLVKIISP KNNPPTIVQDKVLALIQAWA DAFRSSPDLT GVVHIYEELK RKGVEFPMADLDALSPIHTP QRSVPEVDPA ATMPRSQSQQ RTSAGSYSSPPPAPYSAPQA PALSVTGPIT ANSEQIARLR SELDVVRGNT KVMSEMLTEM VPGQEDSSDL ELLQELNRTCRAMQQRIVEL ISRVSNEEVT EELLHVNDDL NNVFLRYERF ERYRSGRSVQ NASNGVLNEV TEDNLIDLGP GSPAVVSPMVGNTAPPSSLS SQLAGLDLGT ESVSGTLSSL QQCNPRDGFD MFAQTRGNSL AEQRKTVTYE DPQAVGGLASALDNRKQSSE GIPVAQPSVM DDIEVWLRTD LKGDDLEEGV TSEEFDKFLE ERAKAAEMVP DLPSPPMEAPAPASNPSGRK KPERSEDALF AL
Sequence Length
439
Solubility
It is recommended to reconstitute the lyophilized Myc in sterile PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Related Product Information for MYC recombinant protein
Description: Myc Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 439 amino acids and having a molecular mass of 48.8kDa.The Myc is fused to a C-terminal poly-arginine tag and purified by proprietary chromatographic techniques.
Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Product Categories/Family for MYC recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
48,846 Da
NCBI Official Full Name
MYC
NCBI Official Symbol
MYC
NCBI Protein Information
myc proto-oncogene protein; proto-oncogene c-Myc; transcription factor p64; v-myc myelocytomatosis viral oncogene homolog
UniProt Protein Name
Myc proto-oncogene protein
Protein Family
UniProt Gene Name
MYC
UniProt Entry Name
MYC_PANTR
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Product Notes
The MYC myc (Catalog #AAA144388) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHHSSGLVPR GSH MGSEFM EFLL GNPFSTPVGQ CLEKATDGSL QSEDWTLNME ICDIINETEE GPKDAIRALK KRLNGNRNYR EVMLALTVLE TCVKNCGHRF HILVANRDFI DSVLVKIISP KNNPPTIVQD KVLALIQAWA DAFRSSPDLT GVVHIYEELK RKGVEFPMAD LDALSPIHTP QRSVPEVDPA ATMPRSQSQQ RTSAGSYSSP PPAPYSAPQA PALSVTGPIT ANSEQIARLR SELDVVRGNT KVMSEMLTEM VPGQEDSSDL ELLQELNRTC RAMQQRIVEL ISRVSNEEVT EELLHVNDDL NNVFLRYERF ERYRSGRSVQ NASNGVLNEV TEDNLIDLGP GSPAVVSPMV GNTAPPSSLS SQLAGLDLGT ESVSGTLSSL QQCNPRDGFD MFAQTRGNSL AEQRKTVTYE DPQAVGGLAS ALDNRKQSSE GIPVAQPSVM DDIEVWLRTD LKGDDLEEGV TSEEFDKFLE ERAKAAEMVP DLPSPPMEAP APASNPSGRK KPERSEDALF AL. It is sometimes possible for the material contained within the vial of "V-Myc Myelocytomatosis Viral Oncogene, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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