(Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1) Recombinant Protein | MX1 recombinant protein
Recombinant Macaca mulatta (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
(Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1); Recombinant Macaca mulatta (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1); Recombinant (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1); Interferon-induced GTP-binding protein Mx1; Myxoma resistance protein 1 Myxovirus resistance protein 1 Cleaved into the following chain: 1. Interferon-induced GTP-binding prote; MX1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-661
Sequence
VLSEVDIVKADPAAASQPLLLNGDADVAQKSPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDEWRGKVSYQDYEIEILDASEVEKEINKAQNTIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPPDIGYKIKTLIRKYIQRQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFEDHPHFRDLLEEGKATIPCLAEKLTSELIAHICKSLPLLENQIKESHQGITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALIQGEETVGEDDSRLFTRLRREFHKWGIIIENNLQEGHKITSRKMQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVNMLHTVTDMVRLAFTDVSMKNFEELFNLHRTAKSKIEDIRTEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDIGTFQPSSTESSMEEIFQHLMAYHQEASKRISSHIPLVIQFFMLQMYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
Sequence Length
661
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,431 Da
NCBI Official Full Name
interferon-induced GTP-binding protein Mx1
NCBI Official Symbol
MX1
NCBI Protein Information
interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus resistance protein 1
UniProt Protein Name
Interferon-induced GTP-binding protein Mx1
Protein Family
UniProt Gene Name
MX1
UniProt Entry Name
MX1_MACMU
Uniprot Description
Function: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens
By similarity.May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation
By similarity.
Subunit structure: Oligomerizes (via the stalk domain) in a criss-cross pattern to form a linear stalk filament, may form ring-like structures with a 24 Angstrom inner diameter. Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7
By similarity.
Subcellular location: Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
By similarity. Note: Binds preferentially to negatively charged phospholipids
By similarity.
Induction: By type I and type III interferons.
Sequence similarities: Belongs to the dynamin family.Contains 1 GED domain.
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Product Notes
The MX1 mx1 (Catalog #AAA968183) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-661. The amino acid sequence is listed below: VLSEVDIVKA DPAAASQPLL LNGDADVAQK SPGSVAENNL CSQYEEKVRP CIDLIDSLRA LGVEQDLALP AIAVIGDQSS GKSSVLEALS GVALPRGSGI VTRCPLVLKL KKLVNEDEWR GKVSYQDYEI EILDASEVEK EINKAQNTIA GEGMGISHEL ITLEISSRDV PDLTLIDLPG ITRVAVGNQP PDIGYKIKTL IRKYIQRQET INLVVVPSNV DIATTEALSM AQEVDPEGDR TIGILTKPDL VDKGTEDKVV DVVRNLVFHL KKGYMIVKCR GQQEIQDQLS LSEALQREKI FFEDHPHFRD LLEEGKATIP CLAEKLTSEL IAHICKSLPL LENQIKESHQ GITEELQKYG VDIPEDENEK MFFLIDKINA FNQDITALIQ GEETVGEDDS RLFTRLRREF HKWGIIIENN LQEGHKITSR KMQKFENQYR GRELPGFVNY RTFETIVKQQ IKALEEPAVN MLHTVTDMVR LAFTDVSMKN FEELFNLHRT AKSKIEDIRT EQEREGEKLI RLHFQMEQIV YCQDQVYRGA LQKVREKELE EEKKKKSWDI GTFQPSSTES SMEEIFQHLM AYHQEASKRI SSHIPLVIQF FMLQMYGQQL QKAMLQLLQD KDTYSWLLKE RSDTSDKRKF LKERLARLTQ ARRRLAQFPG. It is sometimes possible for the material contained within the vial of "(Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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