Murinoglobulin-2 (Mug2) Recombinant Protein | Mug2 recombinant protein

Recombinant Rat Murinoglobulin-2 (Mug2) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Murinoglobulin-2 (Mug2); Recombinant Rat Murinoglobulin-2 (Mug2); partial; Mug2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1448

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 50657404
• NCBI GeneID: 408236
• NCBI Accession #: NP_001002826.1
• NCBI GenBank Nucleotide #: NM_001002826.1
• UniProt Accession #: Q6IE52
• Molecular Weight: 161,589 Da
• NCBI Official Full Name: murinoglobulin-2
• NCBI Official Synonym Full Names: murinoglobulin 2
• NCBI Official Symbol: Mug2
• NCBI Protein Information: murinoglobulin-2
• UniProt Protein Name: Murinoglobulin-2
• Protein Family: Murinoglobulin
• UniProt Gene Name: Mug2

NCBI Description

member of the alpha 2 macroglobulin family [RGD, Feb 2006]

Uniprot Description

A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.