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Male-specific lethal 3 homolog (Msl3) Recombinant Protein | Msl3 recombinant protein

Recombinant Mouse Male-specific lethal 3 homolog (Msl3)

Gene Names
Msl3; Msl31; Msl3l1; AU018931
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Male-specific lethal 3 homolog (Msl3); Recombinant Mouse Male-specific lethal 3 homolog (Msl3); Msl3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-525, Full length protein
Sequence
MSASEGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNRSWDRWAAEEHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLPGVDSVLKSVPVKEKSKNDENSVSSTCHESCGEKNGGIKEHRQRRIKVKAKAKKKVLSLRSRKEMDERTITIDIPDVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHTHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRPNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY
Sequence Length
525
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Msl3 recombinant protein
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,483 Da
NCBI Official Full Name
male-specific lethal 3 homolog
NCBI Official Synonym Full Names
MSL complex subunit 3
NCBI Official Symbol
Msl3
NCBI Official Synonym Symbols
Msl31; Msl3l1; AU018931
NCBI Protein Information
male-specific lethal 3 homolog
UniProt Protein Name
Male-specific lethal 3 homolog
Protein Family
UniProt Gene Name
Msl3
UniProt Synonym Gene Names
Msl31; Msl3l1; MSL3-like 1

Uniprot Description

May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex ().

Research Articles on Msl3

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Product Notes

The Msl3 msl3 (Catalog #AAA1415381) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-525, Full length protein. The amino acid sequence is listed below: MSASEGMKFQ FHSGEKVLCF EPDPTKARVL YDAKIIDVII GKDEKGRKIP EYLIHFNGWN RSWDRWAAEE HVLHDTDENR RLQRKLAKKA IARLRGTGKK KRRCRLPGVD SVLKSVPVKE KSKNDENSVS STCHESCGEK NGGIKEHRQR RIKVKAKAKK KVLSLRSRKE MDERTITIDI PDVLKKQLED DCYYINRRKR LVKLPCQTNI ITILESYVKH FAINAAFSAN ERPRHHHAMM HTHMNVHYVP AEKNVDLCKE MVDGLRITFD YTLPLVLLYP YEQTQYKRVT SSKFFLPIKE STTTTNRSQE ELSPSPPLLN PSTPQSTESQ PPTGEPATPK RRKAEPEALQ SLRRSTRHST NCDRLSESSS SPQPKRRQQD TSASMPKLFL HLEKKTPVHS RSSSPIPLTP SKDGSAVFAG FEGRRPNEIN EVLSWKLVPD NYPPGDQPPP PSYIYGAQHL LRLFVKLPEI LGKMSFSEKN LKALLKHFDL FLRFLAEYHD DFFPESAYVA ACEAHYSTKN PRAIY. It is sometimes possible for the material contained within the vial of "Male-specific lethal 3 homolog (Msl3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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