Mouse mutS homolog 5 (E. coli) ELISA Kit | MSH5 elisa kit
Mouse MutS protein homolog 5, MSH5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogenesis in males and complete loss of ovarian structures in females. Mutations in a similar gene in humans have been shown to cause common variable immune deficiency (CVID) and immunoglobulin A deficiency. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
MSH5: Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis. Belongs to the DNA mismatch repair MutS family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Cellular Component: synaptonemal complex
Molecular Function: DNA-dependent ATPase activity; DNA binding; nucleotide binding; ATP binding; mismatched DNA binding
Biological Process: mismatch repair; homologous chromosome segregation; meiotic cell cycle; meiotic recombination; synapsis; female gamete generation; chiasma formation; meiosis I
Research Articles on MSH5
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Product Notes
The Mouse MSH5 msh5 (Catalog #AAA9336518) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336518 ELISA Kit recognizes Mouse MSH5. It is sometimes possible for the material contained within the vial of "mutS homolog 5 (E. coli), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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