High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2) Recombinant Protein | Ms4a2 recombinant protein

Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2), partial

Cat. Num. AAA955475

• Gene Names: Ms4a2; FcRB; Fce1b; Ms4a1; fcERI; Fcer1b; Fcrbeta
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2); Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2); partial; Ms4a2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-235
• Sequence: MDTENRSRADLALPNPQESSSAPDIELLEASPAKAAPPKQTWRTFLKKELEFLGATQILVGLICLCFGTIVCSVLYVSDFDEEVLLLYKLGYPFWGAVLFVLSGFLSIISERKNTLYLVRGSLGANIVSSIAAGTGIAMLILNLTNNFAYMNNCKNVTEDDGCFVASFTTELVLMMLFLTILAFCSAVLFTIYRIGQELESKKVPDDRLYEELNVYSPIYSELEDKGETSSPVDS
• Sequence Length: 235

• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 7305049
• NCBI GeneID: 14126
• NCBI Accession #: NP_038544.1
• NCBI GenBank Nucleotide #: NM_013516.2
• UniProt Accession #: P20490
• Molecular Weight: 25,963 Da
• NCBI Official Full Name: high affinity immunoglobulin epsilon receptor subunit beta isoform a
• NCBI Official Synonym Full Names: membrane-spanning 4-domains, subfamily A, member 2
• NCBI Official Symbol: Ms4a2
• NCBI Official Synonym Symbols: FcRB; Fce1b; Ms4a1; fcERI; Fcer1b; Fcrbeta
• NCBI Protein Information: high affinity immunoglobulin epsilon receptor subunit beta
• UniProt Protein Name: High affinity immunoglobulin epsilon receptor subunit beta
• Protein Family: High affinity immunoglobulin epsilon receptor
• UniProt Gene Name: Ms4a2
• UniProt Synonym Gene Names: Fce1b; Fcer1b; Ms4a1; FcERI

NCBI Description

This gene encodes a member of the membrane-spanning 4A family. The encoded protein is the beta subunit of the high affinity IgE receptor and is localized to the membrane. The encoded protein is required for full activation of mast cells, including the release of histamine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Description

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.