High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2) Recombinant Protein | Ms4a2 recombinant protein
Recombinant Rat High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
beta chain of the high affinity receptor for immunoglobulin E [RGD, Feb 2006]
Uniprot Description
FcER1B: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy. Belongs to the MS4A family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, misc.
Cellular Component: endosome; external side of plasma membrane; Fc-epsilon receptor I complex; integral to plasma membrane; lipid raft
Molecular Function: IgE binding; IgE receptor activity; phosphoprotein binding; protein kinase binding; SH2 domain binding
Biological Process: cell surface receptor linked signal transduction; cytokine secretion; immune response; inflammatory response; phospholipase C activation; positive regulation of mast cell degranulation; protein kinase C activation; regulation of release of sequestered calcium ion into cytosol; signal transduction
Research Articles on Ms4a2
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Product Notes
The Ms4a2 ms4a2 (Catalog #AAA7020833) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-243aa; Full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Ms4a2 ms4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDTENKSRAD LALPNPQESP SAPDIELLEA SPPAKALPEK PASPPPQQTW QSFLKKELEF LGVTQVLVGL ICLCFGTVVC STLQTSDFDD EVLLLYRAGY PFWGAVLFVL SGFLSIMSER KNTLYLVRGS LGANIVSSIA AGLGIAILIL NLSNNSAYMN YCKDITEDDG CFVTSFITEL VLMLLFLTIL AFCSAVLLII YRIGQEFERS KVPDDRLYEE LHVYSPIYSA LEDTREASAP VVS. It is sometimes possible for the material contained within the vial of "High affinity immunoglobulin epsilon receptor subunit beta (Ms4a2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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