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Human Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit | MPO-ANCA IgG elisa kit

Human Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit

Gene Names
PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
Reactivity
Human
Synonyms
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG; Human Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit; MPO-ANCA IgG elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Sequence Length
256
Assay Type
Sandwich (Quantitative)
Detection Range
0.25ng/ml-8ng/ml.
Sensitivity
0.1ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for MPO-ANCA IgG elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MPOAC-IgG (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,807 Da
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
PRTN3
NCBI Official Synonym Symbols
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
NCBI Protein Information
myeloblastin; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein 7; serine proteinase, neutrophil; Wegener granulomatosis autoantigen
UniProt Protein Name
Myeloblastin
UniProt Gene Name
PRTN3
UniProt Synonym Gene Names
MBN; PR-3; PR3; NP-4
UniProt Entry Name
PRTN3_HUMAN

Uniprot Description

PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: EC 3.4.21.76; Protease; Cell cycle regulation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular matrix; extracellular space; plasma membrane; cytosol

Molecular Function: enzyme binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: collagen catabolic process; negative regulation of phagocytosis; positive regulation of cell proliferation; blood coagulation; proteolysis

Research Articles on MPO-ANCA IgG

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Product Notes

The Human MPO-ANCA IgG prtn3 (Catalog #AAA015194) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA015194 ELISA Kit recognizes Human MPO-ANCA IgG. It is sometimes possible for the material contained within the vial of "Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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