Porcine Myeloid Progenitor Inhibitory Factor 1 ELISA Kit | MPIF-1 elisa kit

Porcine Myeloid Progenitor Inhibitory Factor 1 ELISA Kit

Cat. Num. AAA734897

• Gene Names: CCL23; CKb8; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; hmrp-2a; CK-BETA-8
• Reactivity: Porcine
• Synonyms: Myeloid Progenitor Inhibitory Factor 1; Porcine Myeloid Progenitor Inhibitory Factor 1 ELISA Kit; MPIF-1 elisa kit

• Reactivity: Porcine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for MPIF-1 elisa kit

Neurobiology

NCBI and Uniprot Product Information

• NCBI GI #: 1916250
• NCBI GeneID: 6368
• Molecular Weight: 15,290 Da
• NCBI Official Full Name: MPIF-1
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 23
• NCBI Official Symbol: CCL23
• NCBI Official Synonym Symbols: CKb8; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; hmrp-2a; CK-BETA-8
• NCBI Protein Information: C-C motif chemokine 23; C6 beta-chemokine; macrophage inflammatory protein 3; myeloid progenitor inhibitory factor 1; small inducible cytokine subfamily A (Cys-Cys), member 23
• UniProt Protein Name: C-C motif chemokine 23
• UniProt Gene Name: CCL23
• UniProt Synonym Gene Names: MIP3; MPIF1; SCYA23; CKB-8; MIP-3; MPIF-1
• UniProt Entry Name: CCL23_HUMAN

NCBI Description

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; monocyte chemotaxis; cell-cell signaling; immune response; inflammatory response; chemotaxis; signal transduction