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Mouse Interleukin-2 Antibody | anti-IL-2r antibody

Mouse Anti Human Interleukin-2 receptor

Applications
Flow Cytometry, Functional Assay
Purity
Ion Exchange.
Synonyms
Interleukin-2; Mouse Anti Human Interleukin-2 receptor; IL 2r Antibody; Interleukin-2 Receptor (CD25); Mouse Anti-Human; CD25; IL2R; TCGFR; IL-2RA; sIL-2RA; TAC antigen; sIL-2R; IDDM10; p55 TypeMouse Anti Human Monoclonal; anti-IL-2r antibody
Ordering
For Research Use Only!
Host
Mouse
Isotype
IgG2a
Clone Number
YNRhIL2R
Purity/Purification
Ion Exchange.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
21
Applicable Applications for anti-IL-2r antibody
Flow Cytometry (FC/FACS)
Application Notes
1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2 and will stain 70% of PHA-activated human T cells (by FACS) 10 ul will stain 106 IL-2R positive cells for FACS analysis or sorting.
Reconstitution
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
Con A-activated human T cells.
Preparation and Storage
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Related Product Information for anti-IL-2r antibody
Introduction: IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas.
Product Categories/Family for anti-IL-2r antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
30,723 Da
NCBI Official Full Name
interleukin 2 receptor, partial
UniProt Protein Name
Interleukin-2 receptor subunit alpha
Protein Family
UniProt Gene Name
Il2ra
UniProt Synonym Gene Names
Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA
UniProt Entry Name
IL2RA_MOUSE

Uniprot Description

IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; interleukin-2 receptor activity; drug binding; interleukin-2 binding

Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; negative regulation of T cell proliferation; inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; negative regulation of inflammatory response; immune response; positive regulation of T cell proliferation; T cell homeostasis; activated T cell apoptosis

Similar Products

Product Notes

The IL-2r il2ra (Catalog #AAA140005) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Interleukin-2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). 1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2 and will stain 70% of PHA-activated human T cells (by FACS) 10 ul will stain 106 IL-2R positive cells for FACS analysis or sorting. Researchers should empirically determine the suitability of the IL-2r il2ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin-2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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