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Immunoprecipitation (IP) (IP Result of anti-CD206 (IP: MBS7607344, 5ug; Detection: MBS7607344 1:500) with human placenta tissue lysate 1400ug.)

Mouse CD206 Antibody | anti-CD206 antibody

Anti-CD206 Antibody

Gene Names
MRC1; MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
>=95% as determined by SDS-PAGE
Protein A+G Purification
Synonyms
CD206; Anti-CD206 Antibody; CLEC13D; Macrophage mannose receptor 1; Mannose receptor; mannose receptor; C type 1; MMR; MRC1; anti-CD206 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Isotype
IgG2a
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G Purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Sequence Length
1456
Applicable Applications for anti-CD206 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
WB: 1:1000-1:4000
IP: 1:200-1:1000
Immunogen
CD206
Preparation and Storage
Store at -20 degree C for 24 months. Avoid repeated freeze/thaw cycles.

Immunoprecipitation (IP)

(IP Result of anti-CD206 (IP: MBS7607344, 5ug; Detection: MBS7607344 1:500) with human placenta tissue lysate 1400ug.)

Immunoprecipitation (IP) (IP Result of anti-CD206 (IP: MBS7607344, 5ug; Detection: MBS7607344 1:500) with human placenta tissue lysate 1400ug.)

Western Blot (WB)

(human liver tissue were subjected to SDS PAGE followed by western blot with MBS7607344 (CD206 antibody) at dilution of 1:2000)

Western Blot (WB) (human liver tissue were subjected to SDS PAGE followed by western blot with MBS7607344 (CD206 antibody) at dilution of 1:2000)
Related Product Information for anti-CD206 antibody
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60 kDa
NCBI Official Full Name
macrophage mannose receptor 1
NCBI Official Synonym Full Names
mannose receptor C-type 1
NCBI Official Symbol
MRC1
NCBI Official Synonym Symbols
MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
NCBI Protein Information
macrophage mannose receptor 1
UniProt Protein Name
Macrophage mannose receptor 1
UniProt Gene Name
MRC1
UniProt Synonym Gene Names
CLEC13D; CLEC13DL; MRC1L1; MMR
UniProt Entry Name
MRC1_HUMAN

NCBI Description

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Uniprot Description

MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10p12.33

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane

Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity

Biological Process: receptor-mediated endocytosis; signal transduction

Research Articles on CD206

Similar Products

Product Notes

The CD206 mrc1 (Catalog #AAA7607344) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD206 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD206 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). WB: 1:1000-1:4000 IP: 1:200-1:1000. Researchers should empirically determine the suitability of the CD206 mrc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD206, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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