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Western Blot (WB) (Western blotting analysis (reducing conditions) of microtubules partially purified from porcine brain lysate.Lane 1: immunostaining with anti-MAP2ab (MT-01; 11-253-C100)Lane 2: immunostaining with anti-MAP2ab (MT-07)Lane 3: immunostaining with anti-MAP2ab (MT-08))

Mouse MAP2 Antibody | anti-MAP2 antibody

Anti-MAP2 Purified

Gene Names
MAP2; MAP-2; MAP2A; MAP2B; MAP2C
Reactivity
Human, Mouse, Pig
Applications
Immunoprecipitation, Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
MAP2; Anti-MAP2 Purified; microtubule associated protein 2; Microtubule-associated protein 2; MAP-2; anti-MAP2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Pig
Isotype
IgG1
Clone Number
MT-07
Specificity
The antibody MT-07 recognizes an epitope (aa 1375-1395) located in central domain of molecule Microtubule Associated Protein 2ab (MAP2ab), an intracellular antigen.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
1827
Applicable Applications for anti-MAP2 antibody
Immunoprecipitation, Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), ELISA (EIA)
Immunogen
Microtubule protein (bovine brain) enriched for kinesin
Preparation and Storage
Store at 2-8 degree C.

Western Blot (WB)

(Western blotting analysis (reducing conditions) of microtubules partially purified from porcine brain lysate.Lane 1: immunostaining with anti-MAP2ab (MT-01; 11-253-C100)Lane 2: immunostaining with anti-MAP2ab (MT-07)Lane 3: immunostaining with anti-MAP2ab (MT-08))

Western Blot (WB) (Western blotting analysis (reducing conditions) of microtubules partially purified from porcine brain lysate.Lane 1: immunostaining with anti-MAP2ab (MT-01; 11-253-C100)Lane 2: immunostaining with anti-MAP2ab (MT-07)Lane 3: immunostaining with anti-MAP2ab (MT-08))
Related Product Information for anti-MAP2 antibody
MAP2a and 2b (270 kDa) being found mostly in dendrites, stabilize microtubules (shift the reaction kinetics in addition of new subunits and microtubule growth) and participate in determining the structure of different parts of vertebrate nerve cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
microtubule-associated protein 2 isoform 1
NCBI Official Synonym Full Names
microtubule associated protein 2
NCBI Official Symbol
MAP2
NCBI Official Synonym Symbols
MAP-2; MAP2A; MAP2B; MAP2C
NCBI Protein Information
microtubule-associated protein 2
UniProt Protein Name
Microtubule-associated protein 2
UniProt Gene Name
MAP2
UniProt Synonym Gene Names
MAP-2
UniProt Entry Name
MTAP2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft

Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity

Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development

Research Articles on MAP2

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Product Notes

The MAP2 map2 (Catalog #AAA1801389) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-MAP2 Purified reacts with Human, Mouse, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's MAP2 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation, Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), ELISA (EIA). Researchers should empirically determine the suitability of the MAP2 map2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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