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Western Blot (WB) (Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.)

Mouse anti-Human NKX3A Antibody | anti-NKX3A antibody

NKX3A Antibody

Gene Names
NKX3-1; NKX3; BAPX2; NKX3A; NKX3.1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, ELISA
Synonyms
NKX3A; NKX3A Antibody; NKX3; BAPX2; NKX3.1; NKX3-1; anti-NKX3A antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
4H4
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
159
Applicable Applications for anti-NKX3A antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human NKX3A expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.

Western Blot (WB)

(Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.)

Western Blot (WB) (Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.)

Immunohistochemistry (IHC)

(Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.)

Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.)

Immunohistochemistry (IHC)

(Figure 3: Immunohistochemical analysis of paraffin-embedded human Liver tissues using NKX3A mAb)

Immunohistochemistry (IHC) (Figure 3: Immunohistochemical analysis of paraffin-embedded human Liver tissues using NKX3A mAb)
Related Product Information for anti-NKX3A antibody
Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26.3kDa
NCBI Official Full Name
homeobox protein Nkx-3.1 isoform 2
NCBI Official Synonym Full Names
NK3 homeobox 1
NCBI Official Symbol
NKX3-1
NCBI Official Synonym Symbols
NKX3; BAPX2; NKX3A; NKX3.1
NCBI Protein Information
homeobox protein Nkx-3.1
UniProt Protein Name
Homeobox protein Nkx-3.1
UniProt Gene Name
NKX3-1
UniProt Synonym Gene Names
NKX3.1; NKX3A

NCBI Description

This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Research Articles on NKX3A

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Product Notes

The NKX3A nkx3-1 (Catalog #AAA850643) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NKX3A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NKX3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:200-1:1000 FC: 1:200-1:400 ELISA: 1:10000. Researchers should empirically determine the suitability of the NKX3A nkx3-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKX3A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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