Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Tonsil stained with MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468).)
Mouse anti-Human MCM7 Antibody | anti-MCM7 antibody
MCM7 (Proliferation Marker)
Immunohistochemistry (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Tonsil stained with MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468).)
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Tonsil stained with MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468).)
SDS-Page
(SDS-PAGE Analysis Purified MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468). Confirmation of Integrity and Purity of Antibody.)
SDS-Page
(SDS-PAGE Analysis Purified MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468). Confirmation of Integrity and Purity of Antibody.)
Western Blot (WB)
(Western Blot Analysis of MCF-7, HEK-293, A549, SKBr3, HeP2 cell lysates using MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468).)
Western Blot (WB)
(Western Blot Analysis of MCF-7, HEK-293, A549, SKBr3, HeP2 cell lysates using MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468).)
Testing Data
(Analysis of Protein Array containing more than 19,000 full-length human proteins using MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.)
Testing Data
(Analysis of Protein Array containing more than 19,000 full-length human proteins using MCM7 Recombinant Mouse Monoclonal Antibody (rMCM7/1468) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Research Articles on MCM7
Similar Products
Product Notes
The MCM7 mcm7 (Catalog #AAA4381082) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MCM7 (Proliferation Marker) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCM7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. WB: 1-2ug/ml Immunohistochemistry (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes). Researchers should empirically determine the suitability of the MCM7 mcm7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCM7, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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