Western Blot (WB)
(Figure 1: Western blot analysis using ICAM1 mouse mAb against ICAM1-hIgGFc transfected HEK293 (1) cell lysate.)
Mouse anti-Human ICAM1 Antibody | anti-ICAM1 antibody
ICAM1 Antibody
Gene Names
ICAM1; BB2; CD54; P3.58
Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
ICAM1; ICAM1 Antibody; BB2; CD54; P3.58; anti-ICAM1 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
6G12
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
532
Applicable Applications for anti-ICAM1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:10000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Western Blot (WB)
(Figure 1: Western blot analysis using ICAM1 mouse mAb against ICAM1-hIgGFc transfected HEK293 (1) cell lysate.)
Western Blot (WB)
(Figure 1: Western blot analysis using ICAM1 mouse mAb against ICAM1-hIgGFc transfected HEK293 (1) cell lysate.)
Related Product Information for anti-ICAM1 antibody
ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Product Categories/Family for anti-ICAM1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57.8kDa
NCBI Official Full Name
intercellular adhesion molecule 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 1
NCBI Official Symbol
ICAM1
NCBI Official Synonym Symbols
BB2; CD54; P3.58
NCBI Protein Information
intercellular adhesion molecule 1
UniProt Protein Name
Intercellular adhesion molecule 1
Protein Family
UniProt Gene Name
ICAM1
UniProt Synonym Gene Names
ICAM-1
NCBI Description
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Research Articles on ICAM1
Similar Products
Product Notes
The ICAM1 icam1 (Catalog #AAA850134) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ICAM1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ICAM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the ICAM1 icam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ICAM1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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