Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Urotensin-2 (UTS2) Standard Curve.)
Mouse Urotensin-2 (UTS2) ELISA Kit | UTS2 elisa kit
Mouse Urotensin-2 (UTS2) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Urotensin-2 (UTS2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Urotensin-2 (UTS2) Standard Curve.)
Background: Urotensin-II (U-II) is a peptide ligand, initially isolated from the neurosecretory system of the Goby fish (Gillichthys mirabilis) Bern et al. 1969. For many years it was thought that U-II does not exhibit significant effects in mammalian systems; a view quickly overturned when it was demonstrated that Goby U-II produces slow relaxation of mouse annococygeus muscle, in addition to contraction of rat artery segments. In 1998, the cDNA encoding a U-II precursor was cloned in humans, unequivocally demonstrating its existence in mammalian species.As with other peptide ligands, U-II is synthesised from a larger precursor molecule, known as Prepro-urotensin-II, two isoforms have been identified in man of lengths 124 and 139 residues. Cleavage of either of these precursors produces identical, eleven residue, mature U-II peptides.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the urotensin family of peptide hormones. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone before secretion into the plasma. Mice lacking the encoded protein have a significantly decreased low density lipoprotein cholesterol profile and hepatic steatosis that is consistent with decreased hepatocyte de novo cholesterol synthesis and apolipoprotein B secretion. [provided by RefSeq, Sep 2016]
Uniprot Description
UTS2: Highly potent vasoconstrictor. Belongs to the urotensin-2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4|4 E2
Cellular Component: extracellular region; extracellular space
Molecular Function: hormone activity
Biological Process: elevation of cytosolic calcium ion concentration; negative regulation of blood pressure; negative regulation of glomerular filtration; negative regulation of heart rate; negative regulation of insulin secretion; positive regulation of angiogenesis; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of collagen biosynthetic process; positive regulation of fibroblast proliferation; positive regulation of heart rate; positive regulation of synaptic transmission, cholinergic; regulation of blood pressure
Research Articles on UTS2
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Product Notes
The Mouse UTS2 uts2 (Catalog #AAA9716644) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716644 ELISA Kit recognizes Mouse UTS2. It is sometimes possible for the material contained within the vial of "Urotensin-2 (UTS2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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