Mouse Tyrosine-protein kinase Fes/Fps (FES) ELISA Kit | FES elisa kit
Mouse Tyrosine-protein kinase Fes/Fps (FES) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Fes: a non-receptor tyrosine kinase of the Fer family. Appears to be involved in normal hematopoiesis as well as the development of acute promyelocytic leukemia. Contains one SH2 and one FCH domain. Four LOF point mutations seen in colorectal cancer. Orthologous to v-fes from feline leukemia virus and v-fps from avian transforming virus. Mutant forms are angiogenic. Promotes survival during differentiation, and may act both to promote and inhibit tumors. May be disrupted in the t(15q+;17q-) found in acute promyelocytic leukemia, but the breakpoint does not occur within the gene.
Protein type: Protein kinase, tyrosine (non-receptor); Protein kinase, TK; Oncoprotein; Kinase, protein; Tumor suppressor; EC 2.7.10.2; TK group; Fer family
Cellular Component: microtubule cytoskeleton; Golgi apparatus; extrinsic to internal side of plasma membrane; cytoskeleton; focal adhesion; membrane; cytoplasm; plasma membrane; cytoplasmic vesicle; cell junction
Molecular Function: transferase activity; protein binding; protein-tyrosine kinase activity; microtubule binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; lipid binding; ATP binding; phosphoinositide binding; protein kinase activity; receptor binding
Biological Process: regulation of mast cell degranulation; epidermal growth factor receptor signaling pathway; regulation of cell adhesion; cell migration; peptidyl-tyrosine phosphorylation; positive regulation of myeloid cell differentiation; positive regulation of microtubule polymerization; protein amino acid autophosphorylation; chemotaxis; protein amino acid phosphorylation; regulation of cell proliferation; regulation of cell shape; centrosome organization and biogenesis; regulation of cell differentiation; innate immune response; cell adhesion; cell differentiation; phosphorylation; microtubule bundle formation
Research Articles on FES
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Product Notes
The Mouse FES fes (Catalog #AAA9331800) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331800 ELISA Kit recognizes Mouse FES. It is sometimes possible for the material contained within the vial of "Tyrosine-protein kinase Fes/Fps (FES), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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