Mouse TRNA-splicing endonuclease subunit Sen2 (TSEN2) ELISA Kit | TSEN2 elisa kit
Mouse TRNA-splicing endonuclease subunit Sen2 (TSEN2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Probably carries the active site for 5'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events ().
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Product Notes
The Mouse TSEN2 tsen2 (Catalog #AAA287392) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA287392 ELISA Kit recognizes Mouse TSEN2. It is sometimes possible for the material contained within the vial of "TRNA-splicing endonuclease subunit Sen2 (TSEN2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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