Typical Testing Data/Standard Curve (for reference only)
Mouse Transforming protein RhoA ELISA Kit | Rhoa elisa kit
Mouse Transforming protein RhoA ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Uniprot Description
RHOA: a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Controls the reorganization of actins into podosomes. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders.
Protein type: Motility/polarity/chemotaxis; Oncoprotein; G protein, monomeric; G protein; G protein, monomeric, Rho
Cellular Component: apical junction complex; axon; cell cortex; cell projection; cytoplasm; cytoskeleton; cytosol; endosome; focal adhesion; intracellular; lamellipodium; membrane; mitochondrion; nucleus; plasma membrane; vesicle
Molecular Function: GDP binding; GTP binding; GTPase activity; myosin binding; nucleotide binding; protein binding; protein domain specific binding; Rho GDP-dissociation inhibitor binding
Biological Process: actin cytoskeleton organization and biogenesis; alpha-beta T cell lineage commitment; androgen receptor signaling pathway; apical junction assembly; beta selection; cell adhesion; cell cycle; cell differentiation; cell division; cell morphogenesis; cell-matrix adhesion; cerebral cortex cell migration; cytoskeleton organization and biogenesis; endothelial cell migration; GTP metabolic process; integrin-mediated signaling pathway; negative chemotaxis; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of neuron apoptosis; negative regulation of neuron differentiation; negative regulation of steroid hormone receptor signaling pathway; positive regulation of actin filament polymerization; positive regulation of alpha-beta T cell differentiation; positive regulation of caspase activity; positive regulation of cell growth; positive regulation of cytokinesis; positive regulation of lipase activity; positive regulation of neuron apoptosis; positive regulation of neuron differentiation; positive regulation of smooth muscle contraction; positive regulation of stress fiber formation; radial glial cell differentiation in the forebrain; regulation of actin cytoskeleton organization and biogenesis; regulation of calcium ion transport; regulation of cell migration; regulation of dendrite development; regulation of osteoblast proliferation; regulation of transcription from RNA polymerase II promoter; response to drug; Rho protein signal transduction; skeletal muscle development; small GTPase mediated signal transduction; stress fiber formation; stress-activated protein kinase signaling pathway
Research Articles on Rhoa
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Product Notes
The Mouse Rhoa rhoa (Catalog #AAA2881648) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881648 ELISA Kit recognizes Mouse Rhoa. It is sometimes possible for the material contained within the vial of "Transforming protein RhoA, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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