Mouse Toll Like Receptor 3 (TLR3) ELISA Kit | TLR3 elisa kit
Mouse Toll Like Receptor 3 (TLR3) Mini Samples ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TLR3: a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. Most abundantly expressed in placenta and pancreas. Restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection. Acts via MyD88 and TRAF6, leading to the activation of NF-kappaB and the production of type I interferon.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 8|8 B1.1
Cellular Component: cell surface; cytoplasm; integral to plasma membrane; intracellular; lysosomal membrane
Molecular Function: double-stranded RNA binding; protein binding; receptor activity
Biological Process: activation of NF-kappaB transcription factor; defense response; defense response to virus; I-kappaB phosphorylation; innate immune response; microglial cell activation; microglial cell activation during immune response; positive regulation of chemokine biosynthetic process; positive regulation of chemokine production; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interferon type I production; positive regulation of interferon-alpha biosynthetic process; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of interferon-gamma biosynthetic process; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of JNK cascade; positive regulation of NF-kappaB import into nucleus; positive regulation of protein amino acid phosphorylation; positive regulation of toll-like receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; regulation of dendritic cell cytokine production; response to dsRNA; response to exogenous dsRNA; response to virus; toll-like receptor signaling pathway
Research Articles on TLR3
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Product Notes
The Mouse TLR3 tlr3 (Catalog #AAA2087948) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2087948 ELISA Kit recognizes Mouse TLR3. It is sometimes possible for the material contained within the vial of "Toll Like Receptor 3 (TLR3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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