Mouse SON DNA binding protein ELISA Kit | SON elisa kit

Mouse Protein SON, SON ELISA Kit

Cat. Num. AAA9323207

• Gene Names: Son; nrebp; C81487; AA409051; AU067731; mKIAA1019; 2900011L12Rik
• Reactivity: Mouse
• Synonyms: SON DNA binding protein; Mouse Protein SON; SON ELISA Kit; Mouse Protein SON (SON) ELISA kit; BASS1; C21orf50; DBP-5; FLJ21099; FLJ33914; KIAA1019; NREBP; SON3; Bax antagonist selected in Saccharomyces 1; NRE-binding protein; SON DNA-binding protein; negative regulatory element-binding protein; SON elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 124358955
• NCBI GeneID: 20658
• NCBI Accession #: NP_849211.3
• NCBI GenBank Nucleotide #: NM_178880.4
• UniProt Accession #: Q9QX47; Q811G3; Q9CQ12; Q9CQK6; E3WC91; E9PXW2; E9Q3H8; E9Q3I0; E9Q6M4; E9Q7G2; E9QAR8; E9QMT0
• Molecular Weight: 265,651 Da
• NCBI Official Full Name: protein SON isoform 1
• NCBI Official Synonym Full Names: Son DNA binding protein
• NCBI Official Symbol: Son
• NCBI Official Synonym Symbols: nrebp; C81487; AA409051; AU067731; mKIAA1019; 2900011L12Rik
• NCBI Protein Information: protein SON; NRE-binding protein; Son cell proliferation protein; negative regulatory element-binding protein
• UniProt Protein Name: Protein SON
• Protein Family: Protein
• UniProt Gene Name: Son
• UniProt Synonym Gene Names: Nrebp; NRE-binding protein
• UniProt Entry Name: SON_MOUSE

Uniprot Description

SON: RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that posses weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that posses weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'- GA[GT]AN[CG][AG]CC-3'. May indirectly repress hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; RNA-binding

Cellular Component: nucleoplasm; nuclear speck; nucleus

Molecular Function: protein binding; RS domain binding; nucleic acid binding; DNA binding; RNA binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of RNA splicing; regulation of cell cycle; RNA splicing; cytokinesis; microtubule cytoskeleton organization and biogenesis; cell cycle; mRNA processing; negative regulation of apoptosis