Typical Testing Data/Standard Curve (for reference only)
Mouse Serine--Pyruvate Aminotransferase (AGXT) ELISA Kit | AGXT elisa kit
Mouse Serine--Pyruvate Aminotransferase (AGXT) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Background/Introduction: Serine:pyruvate (or alanine:glyoxylate) aminotransferase (SPT or AGT) in the liver is unique in that its subcellular distribution is entirely peroxisomal in man and herbivores, and largely mitochondrial in carnivores.
NCBI and Uniprot Product Information
Uniprot Description
AGXT: Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1); also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Protein type: Transferase; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - alanine, aspartate and glutamate; Mitochondrial; EC 2.6.1.51; EC 2.6.1.44; Motility/polarity/chemotaxis
Cellular Component: peroxisomal matrix; mitochondrion; mitochondrial matrix; peroxisome
Molecular Function: transferase activity; amino acid binding; protein homodimerization activity; alanine-glyoxylate transaminase activity; serine-pyruvate transaminase activity; transaminase activity; catalytic activity; pyridoxal phosphate binding; receptor binding
Biological Process: pyruvate biosynthetic process; response to cAMP; glyoxylate catabolic process; metabolic process; glyoxylate metabolic process; glycine biosynthetic process, by transamination of glyoxylate; response to glucocorticoid stimulus; oxalic acid secretion; L-cysteine catabolic process; L-alanine catabolic process
Research Articles on AGXT
Similar Products
Product Notes
The Mouse AGXT agxt (Catalog #AAA9717182) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717182 ELISA Kit recognizes Mouse AGXT. It is sometimes possible for the material contained within the vial of "Serine--Pyruvate Aminotransferase (AGXT), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
