Mouse Proteasome Subunit Beta Type 5 (PSMB5) ELISA Kit | PSMB5 elisa kit

Mouse Proteasome Subunit Beta Type 5 (PSMB5) ELISA Kit

Cat. Num. AAA9902066

• Reactivity: Mouse
• Synonyms: Proteasome Subunit Beta Type 5 (PSMB5); Mouse Proteasome Subunit Beta Type 5 (PSMB5) ELISA Kit; PSMB5 elisa kit

• Reactivity: Mouse
• Sequence Length: 263

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for PSMB5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of PSMB5 (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 160333293
• NCBI GeneID: 29425
• NCBI Accession #: NP_001099197.2
• NCBI GenBank Nucleotide #: NM_001105727.2
• UniProt Accession #: P28075
• Molecular Weight: 28,585 Da
• NCBI Official Full Name: proteasome subunit beta type-5
• NCBI Official Synonym Full Names: proteasome subunit beta 5
• NCBI Official Symbol: Psmb5
• NCBI Protein Information: proteasome subunit beta type-5
• UniProt Protein Name: Proteasome subunit beta type-5
• Protein Family: Proteasome
• UniProt Gene Name: Psmb5

NCBI Description

mouse homolog plays a role in production of peptides for MHC class I antigen presentation [RGD, Feb 2006]

Uniprot Description

PSMB5: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway. Belongs to the peptidase T1B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.25.1; Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 15p13

Cellular Component: centrosome; cytoplasm; nucleoplasm; nucleus; proteasome complex; proteasome core complex

Molecular Function: peptidase activity; threonine endopeptidase activity

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; proteolysis; proteolysis involved in cellular protein catabolic process; response to oxidative stress