Typical Testing Data/Standard Curve (for reference only)
Mouse Parathyroid Hormone Related Protein (PTHrP) ELISA Kit | PTHrP elisa kit
Mouse Parathyroid Hormone Related Protein (PTHrP) ELISA Kit
No significant cross-reactivity or interference between Parathyroid Hormone Related Protein (PTHrP) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the parathyroid family of hormones that possesses distinct paracrine and intracrine signaling roles such as regulation of circulating calcium, transplacental calcium transport, osteoclast inhibition, renal bicarbonate excretion and regulation of apoptosis. The encoded protein undergoes proteolytic processing to generate multiple active peptides with distinct signaling functions. The homozygous deletion of this gene leads to death shortly after birth with a chondrodystrophic phenotype characterized by premature chondrocyte differentiation and accelerated bone formation. [provided by RefSeq, Jul 2015]
Uniprot Description
PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6 G3|6 78.19 cM
Cellular Component: cytoplasm; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular; nucleoplasm; nucleus
Molecular Function: hormone activity; peptide hormone receptor binding
Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; alveolus development; bone mineralization; calcium ion homeostasis; endochondral ossification; endoderm development; epithelial cell differentiation; magnesium ion homeostasis; negative regulation of chondrocyte differentiation; negative regulation of transcription factor activity; osteoblast development; phosphate ion homeostasis; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; protein processing; regulation of chondrocyte differentiation; regulation of gene expression; skeletal system development; surfactant homeostasis
Research Articles on PTHrP
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Product Notes
The Mouse PTHrP pthlh (Catalog #AAA2702527) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2702527 ELISA Kit recognizes Mouse PTHrP. It is sometimes possible for the material contained within the vial of "Parathyroid Hormone Related Protein (PTHrP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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