Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multidrug resistance-associated protein 1 (ABCC1) Standard Curve.)
Mouse Multidrug Resistance-Associated Protein 1 (ABCC1) ELISA Kit | ABCC1 elisa kit
Mouse Multidrug Resistance-Associated Protein 1 (ABCC1) ELISA Kit
Gene Names
Abcc1; MRP; Mrp1; Mdrap; Abcc1a; Abcc1b
Reactivity
Mouse
Synonyms
Multidrug Resistance-Associated Protein 1 (ABCC1); Mouse Multidrug Resistance-Associated Protein 1 (ABCC1) ELISA Kit; ABCC1; ABC29; ABCC; DKFZp686N04233; DKFZp781G125; GS-X; MRP; MRP1; ATP-binding cassette; sub-family C; member 1; LTC4 transporter; leukotriene C(4) transporter; multidrug resistance protein; multiple drug resi; ABCC1 elisa kit
Reactivity
Mouse
Specificity
Mouse Multidrug resistance-associated protein 1 (ABCC1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ABCC1. No significant cross-reactivity or interference between Mouse ABCC1 and analogues was observed.
Sequence Length
1528
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multidrug resistance-associated protein 1 (ABCC1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Multidrug resistance-associated protein 1 (ABCC1) Standard Curve.)
Related Product Information for ABCC1 elisa kit
Description: This Mouse Multidrug resistance-associated protein 1 (ABCC1) ELISA Kit employs a two-site sandwich ELISA to quantitate ABCC1 in samples. An antibody specific for ABCC1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ABCC1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ABCC1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ABCC1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Background: Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
multidrug resistance-associated protein 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
NCBI Official Symbol
Abcc1
NCBI Official Synonym Symbols
MRP; Mrp1; Mdrap; Abcc1a; Abcc1b
NCBI Protein Information
multidrug resistance-associated protein 1
UniProt Protein Name
Multidrug resistance-associated protein 1
Protein Family
UniProt Gene Name
Abcc1
UniProt Synonym Gene Names
Abcc1a; Abcc1b; Mdrap; Mrp; LTC4 transporter
UniProt Entry Name
MRP1_MOUSE
NCBI Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. [provided by RefSeq, Nov 2011]
Research Articles on ABCC1
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Product Notes
The Mouse ABCC1 abcc1 (Catalog #AAA9717138) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717138 ELISA Kit recognizes Mouse ABCC1. It is sometimes possible for the material contained within the vial of "Multidrug Resistance-Associated Protein 1 (ABCC1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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