Mouse Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1) ELISA Kit | MAD1L1 elisa kit
Mouse Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Research Articles on MAD1L1
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Product Notes
The Mouse MAD1L1 mad1l1 (Catalog #AAA9916683) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9916683 ELISA Kit recognizes Mouse MAD1L1. It is sometimes possible for the material contained within the vial of "Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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