Mouse Membrane cofactor protein (CD46) ELISA Kit | CD46 elisa kit
Mouse Membrane cofactor protein (CD46) ELISA Kit
Gene Names
Cd46; Mcp
Reactivity
Mouse
Synonyms
Membrane cofactor protein (CD46); Mouse Membrane cofactor protein (CD46) ELISA Kit; AHUS2; MCP; MGC26544; MIC10; TLX; TRA2.10; CD46 antigen; complement regulatory protein; antigen identified by monoclonal antibody TRA-2-10; complement membrane cofactor protein; measles virus receptor; CD46 elisa kit
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse CD46. No significant cross-reactivity or interference between Mouse CD46 and analogues was observed.
Sequence Length
365
Assay Type
Quantitive Sandwich
Samples
Serum, Plasma, Other Biological Fluids
Detection Wavelength
450 nm
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%)
= SD/meanX100
Intra-Assay
CV
Inter-Assay
CV
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for CD46 elisa kit
Description: This assay employs a two-site sandwich ELISA to quantitate CD46 in samples. An antibody specific for CD46 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD46 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD46 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD46 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Overview: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by a very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. In humans, the gene is located on the long arm of chromosome 11. There is no confimed ligand for CD5. T cells express higher levels of CD5 than B cells. CD5 is upregulated on T cells upon strong activation.
Overview: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by a very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. In humans, the gene is located on the long arm of chromosome 11. There is no confimed ligand for CD5. T cells express higher levels of CD5 than B cells. CD5 is upregulated on T cells upon strong activation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,495 Da
NCBI Official Full Name
membrane cofactor protein
NCBI Official Synonym Full Names
CD46 antigen, complement regulatory protein
NCBI Official Symbol
Cd46
NCBI Official Synonym Symbols
Mcp
NCBI Protein Information
membrane cofactor protein
UniProt Protein Name
Membrane cofactor protein
Protein Family
UniProt Gene Name
Cd46
UniProt Synonym Gene Names
Mcp
Uniprot Description
May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Research Articles on CD46
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Product Notes
The Mouse CD46 cd46 (Catalog #AAA2800190) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2800190 ELISA Kit recognizes Mouse CD46. It is sometimes possible for the material contained within the vial of "Membrane cofactor protein (CD46), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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