Typical Testing Data/Standard Curve (for reference only)

Mouse Lipoxin A4 (LXA4) ELISA Kit | LXA4 elisa kit

Mouse Lipoxin A4 (LXA4) ELISA Kit

Gene Names

FPR2; ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II

Reactivity

Mouse

Synonyms

Lipoxin A4 (LXA4); Mouse Lipoxin A4 (LXA4) ELISA Kit; LXA4 elisa kit

Ordering
Cat. Num. AAA261816 For Research Use Only!

Reactivity

Mouse

Specificity

No cross-reaction with other factors.

Sequence Length

351

Samples

Mouse serum, plasma or cell culture supernatant

Assay Type

Quantitative Sandwich

Detection Range

20 ng/mL-0.312 ng/mL

Sensitivity

Up to 0.06 ng/mL

Intra-assay Precision

<= 8%

Inter-assay Precision

<= 12%

Preparation and Storage

Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

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Related Product Information for LXA4 elisa kit

Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Mouse LXA4 monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and biotinylated antibodies are added into ELISA plate wells and washed out with PBS or TBS after their respective additions to the wells. Then Avidin-peroxidase conjugates are added to the wells in after. TMB substrate is used for coloration after the enzyme conjugate has already been thoroughly washed out of the wells by PBS or TBS. TMB reacts to form a blue product from the peroxidase activity, and finally turns to yellow after addition of the stop solution (Color Reagent C). The color intensity and quantity of target analyte in the sample are positively correlated.

NCBI and Uniprot Product Information

NCBI GI #

1916076

NCBI GeneID

2358

Molecular Weight

38,964 Da

NCBI Official Full Name

lipoxin A4 receptor

NCBI Official Synonym Full Names

formyl peptide receptor 2

NCBI Official Symbol

FPR2

NCBI Official Synonym Symbols

ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II

NCBI Protein Information

N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)

UniProt Protein Name

N-formyl peptide receptor 2

UniProt Gene Name

FPR2

UniProt Synonym Gene Names

FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor

UniProt Entry Name

FPR2_HUMAN

Uniprot Description

FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; chemotaxis; cell motility; cell adhesion; inflammatory response

Research Articles on LXA4

1. We also found that human mast cells expressed the N-formyl-peptide receptor 1 (FPRL1) receptor and FPRL1-specific inhibitor affected pleurocidin-mediated activation of mast cell.

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Product Notes

The Mouse LXA4 fpr2 (Catalog #AAA261816) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA261816 ELISA Kit recognizes Mouse LXA4. It is sometimes possible for the material contained within the vial of "Lipoxin A4 (LXA4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse Lipoxin A4 (LXA4) ELISA Kit | LXA4 elisa kit