Typical Testing Data/Standard Curve (for reference only)
Mouse IGFBP3 ELISA Kit | IGFBP3 elisa kit
Mouse IGFBP3 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
IGFBP3: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted
Cellular Component: extracellular space; extracellular region; nucleus
Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; growth factor binding; fibronectin binding; insulin-like growth factor II binding; protein tyrosine phosphatase activator activity
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of catalytic activity; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; negative regulation of protein amino acid phosphorylation; positive regulation of apoptosis; negative regulation of smooth muscle cell proliferation; regulation of growth; regulation of cell growth; negative regulation of smooth muscle cell migration; protein amino acid phosphorylation; positive regulation of myoblast differentiation
Research Articles on IGFBP3
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Product Notes
The Mouse IGFBP3 igfbp3 (Catalog #AAA824832) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA824832 ELISA Kit recognizes Mouse IGFBP3. AAA Biotech's IGFBP3 can be used in a range of immunoassay formats including, but not limited to, Sandwich ELISA (SE). Researchers should empirically determine the suitability of the IGFBP3 igfbp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGFBP3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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