Typical Testing Data/Standard Curve (for reference only)
Mouse A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit | ADAMTS5 elisa kit
Mouse A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit
No significant cross-reactivity or interference between A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
Uniprot Description
ADAMTS5: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Protein type: EC 3.4.24.-; Extracellular matrix; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 21q21.3
Cellular Component: endoplasmic reticulum lumen; extracellular region; extracellular space; proteinaceous extracellular matrix
Molecular Function: extracellular matrix binding; heparin binding; integrin binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding
Biological Process: defense response to bacterium; extracellular matrix disassembly; proteolysis
Research Articles on ADAMTS5
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Product Notes
The Mouse ADAMTS5 adamts5 (Catalog #AAA2706829) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2706829 ELISA Kit recognizes Mouse ADAMTS5. It is sometimes possible for the material contained within the vial of "A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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