Mouse 4E-BP1 ELISA Kit | 4E-BP1 elisa kit
Phospho-4E-BP1 (Thr69) Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
4E-BP1: binds to eIF4E, preventing its assembly into the EIF4F complex and inhibiting cap-dependent translation. Phosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the PI3 kinase pathway.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 8 A2|8 15.95 cM
Cellular Component: cytoplasm; cytosol; nucleus; protein complex
Molecular Function: eukaryotic initiation factor 4E binding; protein binding; protein phosphatase 2A binding; translation initiation factor binding; translation repressor activity
Biological Process: cellular response to dexamethasone stimulus; cellular response to hypoxia; G1/S transition of mitotic cell cycle; insulin receptor signaling pathway; negative regulation of protein complex assembly; negative regulation of translation; negative regulation of translational initiation; positive regulation of mitotic cell cycle; regulation of translation; regulation of translational initiation; response to amino acid starvation; TOR signaling
Research Articles on 4E-BP1
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Product Notes
The Mouse 4E-BP1 eif4ebp1 (Catalog #AAA9501048) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501048 ELISA Kit recognizes Mouse 4E-BP1. It is sometimes possible for the material contained within the vial of "4E-BP1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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