Typical Testing Data/Standard Curve (for reference only)
Mouse HNRPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) CLIA Kit | HNRPA1 clia kit
Mouse HNRPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) CLIA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to HNRPA1. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for HNRPA1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain HNRPA1, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of HNRPA1. You can calculate the concentration of HNRPA1 in the samples by comparing the RLU value of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
involved in the packaging of pre-mRNA into heterologous nuclear ribonucleoprotein particles and in the transport of poly-A mRNA from the nucleus to the cytoplasm; may modulate splice site selection [RGD, Feb 2006]
Uniprot Description
hnRNP A1: Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication. Identified in the spliceosome C complex. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with SEPT6. Interacts with HCV NS5B and with the 5'-UTR and 3'-UTR of HCV RNA. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear export; RNA-binding; RNA splicing; Spliceosome
Cellular Component: nucleoplasm; spliceosome; intermediate filament cytoskeleton; membrane; cytoplasm; cytosol; ribonucleoprotein complex; nucleus
Molecular Function: mRNA binding; protein binding; single-stranded RNA binding; nucleic acid binding; mRNA 3'-UTR binding; RNA strand annealing activity; RNA binding; nucleotide binding; transcription factor binding; single-stranded DNA binding
Biological Process: alternative nuclear mRNA splicing, via spliceosome; mRNA transport; RNA metabolic process; RNA splicing; male gonad development; nuclear export; nuclear import; positive regulation of action potential; mRNA processing; lung development; transformation of host cell by virus
Research Articles on HNRPA1
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Product Notes
The Mouse HNRPA1 hnrnpa1 (Catalog #AAA2532884) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2532884 CLIA Kit recognizes Mouse HNRPA1. It is sometimes possible for the material contained within the vial of "HNRPA1 (Heterogeneous Nuclear Ribonucleoprotein A1), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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