IFN lambda 2 active protein
IFN lambda 2 protein (Mouse)
Gene Names
Ifnl2; Il28a; IL-28A; EG330496
Applications
User optimized
Purity
> 98% pure
Synonyms
IFN lambda 2; IFN lambda 2 protein (Mouse); IL-28A protein; IL28A protein; IFN lambda 2 protein; IFN gamma-2 protein; Interferon gamma-2 protein; IFN lambda-2; IFN lambda-2 protein; IFN lambda 2 active protein
Host
Mouse
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of IFN Lambda 2 protein corresponding to amino acids MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV.
Sequence Length
193
Applicable Applications for IFN lambda 2 active protein
User optimized
Protein Type
Recombinant
Biological Significance
IFN lambda-1, -2, and -3 (also known as IL29, IL28A and IL28B respectively) are distantly related to the IL10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.
Bioactivity
Determined by its ability to activate STAT following receptor-ligand interaction.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for IFN lambda 2 active protein
Purified recombinant Mouse IFN lambda 2 protein
Product Categories/Family for IFN lambda 2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19.8 kDa
NCBI Official Full Name
interferon lambda-2
NCBI Official Synonym Full Names
interferon lambda 2
NCBI Official Symbol
Ifnl2
NCBI Official Synonym Symbols
Il28a; IL-28A; EG330496
NCBI Protein Information
interferon lambda-2
UniProt Protein Name
Interferon lambda-2
UniProt Gene Name
Ifnl2
UniProt Synonym Gene Names
Il28a; IL-28A
UniProt Entry Name
IFNL2_MOUSE
Uniprot Description
IL28A: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.
Protein type: Secreted; Cytokine; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region
Molecular Function: cytokine activity
Biological Process: positive regulation of immune response; mucosal immune response; JAK-STAT cascade; defense response to virus
Research Articles on IFN lambda 2
Similar Products
Product Notes
The IFN lambda 2 ifnl2 (Catalog #AAA539468) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IFN lambda 2 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the IFN lambda 2 ifnl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of IFN Lambda 2 protein correspond ing to amino acids MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV. It is sometimes possible for the material contained within the vial of "IFN lambda 2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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