Motility protein A (motA) Recombinant Protein | motA recombinant protein
Recombinant Escherichia coli Motility protein A (motA)
NCBI and Uniprot Product Information
NCBI Description
Flagellar regulon. [More information is available at EcoGene: EG10601]. MotA and MotB comprise the stator element of the flagellar motor complex. [More information is available at EcoCyc: EG10601].
Uniprot Description
Function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GMP phosphodiesterase) suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein YcgR and the flagellar stator. Ref.10
Subunit structure: Each stator complex is composed of 4 MotA and 2 MotB subunits; in E.coli 11 to 12 stator complexes can be involved in flagellar rotation. 2 A subunits and 1 B subunit are thought to form a single ion channel, so that each stator complex contains two channels. Interacts with FliG. Interacts with flagellar brake protein YcgR in the flagellar basal bodies (Ref.9). In another study (Ref.10) YcgR was not seen to interact with MotA, but instead with FliM and FliG, also in the flagellar basal body. Ref.9
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the MotA family.
Research Articles on motA
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Product Notes
The motA mota (Catalog #AAA1099124) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-295. The amino acid sequence is listed below: MLILLGYLVV LGTVFGGYLM TGGSLGALYQ PAELVIIAGA GIGSFIVGNN GKAIKGTLKA LPLLFRRSKY TKAMYMDLLA LLYRLMAKSR QMGMFSLERD IENPRESEIF ASYPRILADS VMLDFIVDYL RLIISGHMNT FEIEALMDEE IETHESEAEV PANSLALVGD SLPAFGIVAA VMGVVHALGS ADRPAAELGA LIAHAMVGTF LGILLAYGFI SPLATVLRQK SAETSKMMQC VKVTLLSNLN GYAPPIAVEF GRKTLYSSER PSFIELEEHV RAVKNPQQQT TTEEA. It is sometimes possible for the material contained within the vial of "Motility protein A (motA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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