Mouse WIPI2 Monoclonal Antibody | anti-WIPI2 antibody
MOUSE ANTI WIPI2
Gene Names
Wipi2; 1110018O08Rik; 2510001I10Rik
Applications
Immunofluorescence, Immunoprecipitation, Immunohistochemistry, Western Blot
Synonyms
WIPI2; Monoclonal Antibody; MOUSE ANTI WIPI2; anti-WIPI2 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2A2
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
445
Applicable Applications for anti-WIPI2 antibody
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Buffer Solution
Phosphate buffered saline
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-WIPI2 antibody
Mouse anti Human WIPI2 antibody, clone 2A2 recognies WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2), also known as WIPI49-like protein 2. WIPI2 is a 454 amino acid ~54kDa autophagosomal marker containing three WD repeats. WIPI2 a mammalian orthologue of the yeast protein Atg18 and is similarly recruited to early autophagosomal structures and is required for their maturation into mature autophagosomes (Polson et al. 2010). Mouse anti Human WIPI2 antibody, clone 2A2 has been used for the immunofluorescent detection of WIPI2 in the human retinal epithelial cell line RPE1 (MacVicar and Lane 2014).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,477 Da
NCBI Official Full Name
WD repeat domain phosphoinositide-interacting protein 2
NCBI Official Synonym Full Names
WD repeat domain, phosphoinositide interacting 2
NCBI Official Symbol
Wipi2
NCBI Official Synonym Symbols
1110018O08Rik; 2510001I10Rik
NCBI Protein Information
WD repeat domain phosphoinositide-interacting protein 2; WIPI-2
UniProt Protein Name
WD repeat domain phosphoinositide-interacting protein 2
Protein Family
UniProt Gene Name
Wipi2
UniProt Synonym Gene Names
WIPI-2
UniProt Entry Name
WIPI2_MOUSE
Uniprot Description
WIPI2: Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P. Interacts with TECPR1. Ubiquitously expressed. Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. Belongs to the WD repeat SVP1 family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Autophagy
Cellular Component: nucleoplasm; protein complex; extrinsic to membrane; membrane; pre-autophagosomal structure membrane; cytoplasm; cytosol
Molecular Function: phosphatidylinositol 3-phosphate binding
Biological Process: protein amino acid lipidation; mitochondrion degradation; autophagy; cellular response to nitrogen starvation; autophagic vacuole formation
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Product Notes
The WIPI2 wipi2 (Catalog #AAA224562) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's WIPI2 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB). Researchers should empirically determine the suitability of the WIPI2 wipi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WIPI2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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