Mouse Vitamin D3 Monoclonal Antibody
Vitamin D3 antibody
Applications
Flow Cytometry, Functional Assay
Synonyms
Vitamin D3; Monoclonal Antibody; Vitamin D3 antibody; Monoclonal Vitamin D3; Anti-Vitamin D3; Vitamin D 3; Vitamin D; D3; 25-hydroxy vitamin D3; 25(OH)D3; Vitamin D-3; anti-Vitamin D3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
685503
Form/Format
Supplied lyophilized from a 0.2 mum filtered solution in PBS with Trehalose.
Applicable Applications for anti-Vitamin D3 antibody
Flow Cytometry (FC/FACS)
Biological Significance
25hydroxyvitaminD3 (25(OH)D3) is synthesized in the liver and is the primary circulating form of vitamin D. Its blood concentration, which reflects 25(OH)D3 produced by exposure to ultraviolet B, as well as dietary and vitamin D supplementation, is felt to be the best indicator of vitamin D status. 25(OH)D3 is metabolized to 1 alpha,25(OH)2D3 in the proximal tubular cells of the kidney by the enzyme 1alphahydroxylase. The vitamin D structure is similar to that of classic steroid hormones, such as estradiol, cortisol, and aldosterone in that they have the same root cyclopentanoperhydrophenanthrene ring structure. It has been shown that the active steroid hormone 1alpha,25(OH)2D3 is essential for life in higher animals. Besides playing important roles in calcium homeostasis and bone mineral metabolism, it is now known to play a role in cellular differentiation, inhibition of cell growth, immune regulation and the prevention of neoplastic transformation. The active form of vitamin D3, 1alpha,25(OH)2D3, acts both through its cellular receptor, the vitamin D receptor (VDR), and through other extrarenal targets in an autocrine and paracrine manner where 1alphahydroxylase is present.
Immunogen
Vitamin D3 antibody was raised in mouse using 25-Hydroxyvitamin D3 as the immunogen.
Preparation and Storage
Store at -20 degree to -70 degree C
Related Product Information for anti-Vitamin D3 antibody
mouse monoclonal Vitamin D3 antibody
Product Categories/Family for anti-Vitamin D3 antibody
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Product Notes
The Vitamin D3 (Catalog #AAA833612) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Vitamin D3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the Vitamin D3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vitamin D3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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