Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data (Detection limit for recombinant GST tagged UTRN is 0.1ng/ml using MBS6008391 as a capture antibody.)

Mouse anti-Human Utrophin Monoclonal Antibody | anti-UTRN antibody

Utrophin (UTRN, Dystrophin-related Protein 1, DRP1, DRP-1, DMDL, DRP) (MaxLight 650)

Gene Names
UTRN; DRP; DMDL; DRP1
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Purified
Synonyms
Utrophin; Monoclonal Antibody; Utrophin (UTRN; Dystrophin-related Protein 1; DRP1; DRP-1; DMDL; DRP) (MaxLight 650); anti-UTRN antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
5G6
Specificity
Recognizes human Utrophin.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Sequence Length
3433
Applicable Applications for anti-UTRN antibody
FLISA, Immunofluorescence (IF), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Partial recombinant protein corresponding to aa3328-3433 from human Utrophin with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
LEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPSCCPNVPSRPQAM
Conjugate
MaxLight650
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Testing Data

(Detection limit for recombinant GST tagged UTRN is 0.1ng/ml using MBS6008391 as a capture antibody.)

Testing Data (Detection limit for recombinant GST tagged UTRN is 0.1ng/ml using MBS6008391 as a capture antibody.)

Immunofluorescence (IF)

(Immunofluorescence of HeLa celLauren Shoreusing MBS6008391 (10ug/ml).)

Immunofluorescence (IF) (Immunofluorescence of HeLa celLauren Shoreusing MBS6008391 (10ug/ml).)
Related Product Information for anti-UTRN antibody
Utrophin is a homologue of dystrophin and in normal muscle utrophin expression is restricted to neuromuscular junctions. Interestingly, in dystrophindeficient muscle, utrophin may be upregulated and is also present around the periphery of most muscle fibers. This antibody will help identify utrophin expression in muscle sections.
Product Categories/Family for anti-UTRN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
utrophin isoform 1
NCBI Official Synonym Full Names
utrophin
NCBI Official Symbol
UTRN
NCBI Official Synonym Symbols
DRP; DMDL; DRP1
NCBI Protein Information
utrophin
UniProt Protein Name
Utrophin
Protein Family
UniProt Gene Name
UTRN
UniProt Synonym Gene Names
DMDL; DRP1; DRP-1

NCBI Description

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

May play a role in anchoring the cytoskeleton to the plasma membrane.

Research Articles on UTRN

Similar Products

Product Notes

The UTRN utrn (Catalog #AAA6225396) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Utrophin (UTRN, Dystrophin-related Protein 1, DRP1, DRP-1, DMDL, DRP) (MaxLight 650) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Utrophin can be used in a range of immunoassay formats including, but not limited to, FLISA, Immunofluorescence (IF), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the UTRN utrn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Utrophin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.