Mouse Upstream Transcription Factor-2 Monoclonal Antibody | anti-USF2 antibody

Upstream Transcription Factor-2 (USF2)

Cat. Num. AAA601559

• Gene Names: USF2; FIP; bHLHb12
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Upstream Transcription Factor-2; Monoclonal Antibody; Upstream Transcription Factor-2 (USF2); Anti -Upstream Transcription Factor-2 (USF2); anti-USF2 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8C350
• Specificity: Recognizes human Upstream Transcription Factor-2.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-USF2 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human Upstream Transcription Factor-2
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-USF2 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 29612623
• NCBI GeneID: 7392
• UniProt Accession #: Q15853; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q6FI33; Q6YI47
• Molecular Weight: 36,955 Da
• NCBI Official Full Name: Upstream transcription factor 2, c-fos interacting
• NCBI Official Synonym Full Names: upstream transcription factor 2, c-fos interacting
• NCBI Official Symbol: USF2
• NCBI Official Synonym Symbols: FIP; bHLHb12
• NCBI Protein Information: upstream stimulatory factor 2; FOS-interacting protein; c-fos interacting protein; major late transcription factor 2; class B basic helix-loop-helix protein 12
• UniProt Protein Name: Upstream stimulatory factor 2
• Protein Family: Upstream stimulatory factor
• UniProt Gene Name: USF2
• UniProt Synonym Gene Names: BHLHB12
• UniProt Entry Name: USF2_HUMAN

NCBI Description

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Uniprot Description

USF2: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; protein heterodimerization activity; sequence-specific DNA binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; lactation; regulation of transcription from RNA polymerase II promoter by glucose; lipid homeostasis; late viral mRNA transcription; positive regulation of transcription from RNA polymerase II promoter by glucose; positive regulation of transcription from RNA polymerase II promoter