Western Blot (WB)
(Western Blot detection against Immunogen (37.11kD).)
Mouse anti-Human UNC5D Monoclonal Antibody | anti-UNC5D antibody
UNC5D (Protein Unc-5 Homolog D, Netrin Receptor UNC5D, Protein Unc-5 Homolog 4, UNC5H4, KIAA1777, UNQ6012/PRO34692) (PE)
Gene Names
UNC5D; Unc5h4; PRO34692
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
UNC5D; Monoclonal Antibody; UNC5D (Protein Unc-5 Homolog D; Netrin Receptor UNC5D; Protein Unc-5 Homolog 4; UNC5H4; KIAA1777; UNQ6012/PRO34692) (PE); anti-UNC5D antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4G3
Specificity
Recognizes human UNC5D.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Sequence Length
953
Applicable Applications for anti-UNC5D antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Partial recombinant protein corresponding to aa31-131 from human UNC5D (NP_543148) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
TDNGEALPESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQ
Conjugate
PE
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (37.11kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (37.11kD).)
Testing Data
(Detection limit for recombinant GST tagged UNC5D is ~0.03ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged UNC5D is ~0.03ng/ml as a capture antibody.)
Product Categories/Family for anti-UNC5D antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
netrin receptor UNC5D isoform 1
NCBI Official Synonym Full Names
unc-5 netrin receptor D
NCBI Official Symbol
UNC5D
NCBI Official Synonym Symbols
Unc5h4; PRO34692
NCBI Protein Information
netrin receptor UNC5D
UniProt Protein Name
Netrin receptor UNC5D
Protein Family
UniProt Gene Name
UNC5D
Uniprot Description
Receptor for the netrin NTN4 that promotes neuronal cell survival (). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell ().
Research Articles on UNC5D
Similar Products
Product Notes
The UNC5D unc5d (Catalog #AAA6160986) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The UNC5D (Protein Unc-5 Homolog D, Netrin Receptor UNC5D, Protein Unc-5 Homolog 4, UNC5H4, KIAA1777, UNQ6012/PRO34692) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UNC5D can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the UNC5D unc5d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UNC5D, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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