Western Blot (WB)
()
Mouse UCHL3 Monoclonal Antibody | anti-UCHL3 antibody
UCHL3 antibody
Applications
ELISA, Western Blot
Purity
UCHL3 antibody was purified by ammonium sulfate precipitation
Synonyms
UCHL3; Monoclonal Antibody; UCHL3 antibody; Monoclonal UCHL3; Anti-UCHL3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); BOS_12557; DKEY-57A22.6; rCG_37146; RGD1561196; RP11-173B14.3; ubiquitin carboxyl-terminal esterase L4; ubiquitin carboxyl-terminal hydrolase-6; ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; ubiquitin thiolesterase; UCH-6; UCH-L3; uchl4; anti-UCHL3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
AF9G8
Purity/Purification
UCHL3 antibody was purified by ammonium sulfate precipitation
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Applicable Applications for anti-UCHL3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:2000
Biological Significance
UCHL3 is universally expressed in all tissues, while UCHL1 is expressed exclusively in neuronal tissue, testis and ovary. The activity of UCHL3 is more than 200 fold higher than UCHL1 when a fluorogenic ubiquitin substrate is used. UCHL1 associates with monoubiquitin and UCHL3 binds to Nedd8, ubiquitin-like protein. UCHL1 and UCHL3 play a role in the regulation of neuronal development and spermatogenesis. UCHL1 is involved in the pathogenesis of Parkinson?s disease (PD) and Alzheimer?s disease (AD). Down-regulation and extensive oxidative modification of UCHL1 have been observed in the brains of AD patients as well as PD patients.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
UCHL3 antibody was raised in Mouse using a recombinant human protein purified from E Coli (GST-UCHL3) as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
Western Blot (WB)
()
Western Blot (WB)
()
Related Product Information for anti-UCHL3 antibody
Mouse monoclonal UCHL3 antibody
Product Categories/Family for anti-UCHL3 antibody
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Product Notes
The UCHL3 (Catalog #AAA838103) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's UCHL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the UCHL3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UCHL3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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