Mouse TrpV3 Cation Channel Monoclonal Antibody | anti-Trpv3 antibody
Anti-TrpV3 Cation Channel Monoclonal Antibody
Reactivity
Human, mouse, rat
Applications
Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
TrpV3 Cation Channel; Monoclonal Antibody; Anti-TrpV3 Cation Channel Monoclonal Antibody; anti-Trpv3 antibody
Host
Mouse
Reactivity
Human, mouse, rat
Clonality
Monoclonal
Isotype
lgG2a
Clone Number
S15-4
Specificity
TrpV3 Cation Channel
This antibody recognizes human, mouse, and rat TrpV3.
This antibody recognizes human, mouse, and rat TrpV3.
Form/Format
100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
Sequence Positions
458-474
Applicable Applications for anti-Trpv3 antibody
Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence
Application Notes
Immunoblotting: use at 1-10ug/ml. A band of ~70kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: COS cell lysate transiently transfected with TrpV3.
Antigen
Synthetic peptide corresponding to aa 458-474 (cytoplasmic C-terminus) of rat TrpV3 (accession no. NP_001020928)
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Related Product Information for anti-Trpv3 antibody
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. The TrpV3 protein belongs to a family of nonselective cation channels that function in a variety of processes including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin and are activated at distinct physiological temperatures. The TrpV3 channel is activated at temperatures between 22 and 40 C. The TrpV3 gene is in close proximity to the TrpV1 gene on chromosome 17, and studies suggest that the corresponding two proteins associate with each other to form heteromeric channels.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90,273 Da
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 3
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 3
NCBI Official Symbol
Trpv3
NCBI Protein Information
transient receptor potential cation channel subfamily V member 3; heat sensitive channel TRPV3
UniProt Protein Name
Heat sensitive channel TRPV3
Protein Family
UniProt Gene Name
Trpv3
UniProt Entry Name
Q4QYD9_RAT
Research Articles on Trpv3
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Product Notes
The Trpv3 trpv3 (Catalog #AAA190593) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 458-474. The Anti-TrpV3 Cation Channel Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's TrpV3 Cation Channel can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence. Immunoblotting: use at 1-10ug/ml. A band of ~70kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: COS cell lysate transiently transfected with TrpV3. Researchers should empirically determine the suitability of the Trpv3 trpv3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TrpV3 Cation Channel, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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