Western Blot (WB)
(Western Blot analysis of TRPC5 expression in transfected 293T cell line by TRPC5 monoclonal antibody (M10), clone 1C8.Lane 1: TRPC5 transfected lysate (Predicted MW: 111.4 KDa).Lane 2: Non-transfected lysate.)
Mouse TRPC5 Monoclonal Antibody | anti-TRPC5 antibody
TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5, TRP5) (FITC)
FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of TRPC5 expression in transfected 293T cell line by TRPC5 monoclonal antibody (M10), clone 1C8.Lane 1: TRPC5 transfected lysate (Predicted MW: 111.4 KDa).Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of TRPC5 expression in transfected 293T cell line by TRPC5 monoclonal antibody (M10), clone 1C8.Lane 1: TRPC5 transfected lysate (Predicted MW: 111.4 KDa).Lane 2: Non-transfected lysate.)
Testing Data
(Detection limit for recombinant GST tagged TRPC5 is 1 ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged TRPC5 is 1 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]
Uniprot Description
TRPC5: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC5 sub-subfamily.
Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq23
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: calcium channel activity; protein binding; store-operated calcium channel activity
Biological Process: calcium ion transport; cytosolic calcium ion homeostasis; manganese ion transport; nervous system development
Research Articles on TRPC5
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Product Notes
The TRPC5 trpc5 (Catalog #AAA6178648) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRPC5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TRPC5 trpc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPC5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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