Mouse anti-Human TROP2 Monoclonal Antibody | anti-TACSTD2 antibody
Anti-TROP2 Antibody (Biotin), Mouse Monoclonal
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
TROP2; Monoclonal Antibody; Anti-TROP2 Antibody (Biotin); Mouse Monoclonal; TROP2/TACSTD2 Antibody (Biotin); Mouse MAb; Anti-EGP-1 Antibody; Anti-EGP1 Antibody; Anti-GA733-1 Antibody; Anti-GA7331 Antibody; Anti-GP50 Antibody; Anti-M1S1 Antibody; Anti-TACD2 Antibody; Anti-TROP-2 Antibody; Anti-TROP2 Antibody; tumor-associated calcium signal transducer 2; anti-TACSTD2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
1
Specificity
Human TROP2/TACSTD2
Purity/Purification
Protein A
Form/Format
Liquid. 0.2um filtered solution in PBS
Applicable Applications for anti-TACSTD2 antibody
ELISA (EIA)
Application Notes
ELISA: 0.1-1ug/ml
Immunogen
Recombinant Human TROP2 protein
Conjugation
Biotin
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VEGF165/VEGFA (rh VEGF165/VEGFA; P15692-4; Met1-Arg191). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Related Product Information for anti-TACSTD2 antibody
Background: TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
Product Categories/Family for anti-TACSTD2 antibody
References
Ripani E, et al. (1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int J Cancer. 76(5): 671-6.Wang J, et al. (2008) Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers. Mol Cancer Ther. 7(2): 280-5.
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Product Notes
The TACSTD2 (Catalog #AAA8118947) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-TROP2 Antibody (Biotin), Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TROP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.1-1ug/ml. Researchers should empirically determine the suitability of the TACSTD2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TROP2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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