anti-Human Transferrin Monoclonal Antibody | anti-TF antibody
MAb to Transferrin
Source: Ascites
Human Transferrin
Recommended pairs for transferrin detection by sandwich ELISA:
Capture: MBS311238; Detection: MBS311089
Capture: MBS311238; Detection: MBS311097
Recommended pair for transferrin-transferrin receptor complex detection by sandwich ELISA:
Capture: MBS311096; Detection: MBS311238
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq]
Uniprot Description
Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Subunit structure: Monomer.
Subcellular location: Secreted.
Tissue specificity: Expressed by the liver and secreted in plasma.
Polymorphism: Different polymorphic variants of transferrin are known. The sequence shown is the predominant electrophoretic variant (C1 or TF*C1).
Involvement in disease: Defects in TF are the cause of atransferrinemia (ATRAF) [
MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Ref.4 Ref.39
Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains.
Sequence caution: The sequence AAF22007.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on TF
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Product Notes
The TF tf (Catalog #AAA311238) is an Antibody produced from Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/c mice. Source: Ascites and is intended for research purposes only. The product is available for immediate purchase. The MAb to Transferrin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transferrin can be used in a range of immunoassay formats including, but not limited to, EIA/ELISA, Immunoassay Antibody Pairs. Detection of transferrin in serum and transferrin-transferrin receptor complex by sandwich ELISA. Recommended pairs for transferrin detection by sandwich ELISA: Capture: MBS311238; Detection: MBS311089 Capture: MBS311238; Detection: MBS311097 Recommended pair for transferrin-transferrin receptor complex detection by sandwich ELISA: Capture: MBS311096; Detection: MBS311238. Researchers should empirically determine the suitability of the TF tf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transferrin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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